Publications

O’Neil lab undergraduate researchers marked with *, graduate students marked with #

Rapino, F, Natoli T, Limone, F, O’Connor, E, Blank, J, Tegtmeye,r M, Chen, W, Norabuena, E, Narula, J, Hazelbaker, D, Angelini, G, Barrett, L, O’Neil, AL, Beattie, UK, Thanos, JM, de Rivera, H, Sheridan, SD, Perlis, RH, McCarroll, SA, Stevens, B, Subramanian, A, Nehme, R, Rubin, LL. Small-molecule screen reveals pathways that regulate C4 secretion in stem cell-derived astrocytes. Stem Cell Reports. 2023;18(1):237-53.

Kulick, D*, Moon, E*, Riffe, RM, Teicher, G, Van Deursen, S*, Berson, A*, He, W, Aaron, G, Downes, GB, Devoto, S, O’Neil, AL. Amyotrophic Lateral Sclerosis-Associated Persistent Organic Pollutant cis-Chlordane Causes GABA(A)-Independent Toxicity to Motor Neurons, Providing Evidence toward an Environmental Component of Sporadic Amyotrophic Lateral Sclerosis. ACS Chemical Neuroscience. 2022; 13(24): 3567-3577.

Kumar, MS, Fowler-Magaw, ME, Kulick, D*, Boopathy, S, Gadd, DH, Rotunno, M, Douthwright, C, Golebiowski, D, Yusuf, I, Xu, Z, Brown, RH, Jr., Sena-Esteves, M, O’Neil, AL, Bosco, DA. Anti-SOD1 Nanobodies That Stabilize Misfolded SOD1 Proteins Also Promote Neurite Outgrowth in Mutant SOD1 Human Neurons. International Journal of Molecular Science. 2022; 23(24).

Wells, NGMTillinghast, GAO’Neil, ALSmith, CAFree energy calculations of ALS-causing SOD1 mutants reveal common perturbations to stability and dynamics along the maturation pathwayProtein Science20213018041817.

Andrea Roberts, Alison L. O’Neil, Rachael Barlow, Camille Keeler, William S. Nelligan, and T. David Westmoreland. Chemical Hygiene and Safety Badge for an Upper-Level Laboratory Course. Journal of Chemical Education. 202198 (1), 143-149.

Tomov, M.L., O’Neil, A., Abbasi, H.S. et al. Resolving cell state in iPSC-derived human neural samples with multiplexed fluorescence imagingCommun Biol 4786 (2021).

Alison O’Neil*, Chen Benkler*, Susanah Slepian, Lee Rubin. “Aggregated SOD1 causes selective death of cultured human motor neurons“. Scientific Reports, 2018, (8). *co-first authors

Max Darnell, Alison O’Neil, Luo Gu, Lee Rubin, David Mooney, “Material microenvironmental properties couple to induce distinct transcriptional programs in mammalian stem cells,” PNAS, 2018, 115(36).

Eric Christiansen, Samuel J. Yang, D. Michael Ando, Alison O’Neil, Marc Berndl, Lee  Rubin, Philip Nelson, Steven Finkbeiner, et al., In silico labeling: Predicting fluorescent labels in unlabeled images,” Cell, 2018, 173(3).

Alison O’Neil*, Elizabeth J. Paik*, Shi Yan Ng*, Chicheng Sun, and Lee Rubin (* co-first authors), “Using intracellular markers to identify a novel set of surface markers for live cell purification from a heterogeneous hIPSC culture,” Scientific Reports, 2017, (8). *co-first authors

Patrick Kelly, Prachi Anana, Alexander Uvaydov, Srinivas Chakravartula, Chhime Sherpa, Elena Pires, Alison O’Neil, Trevor Douglas, Mande Holford, “Developing a Dissociative Nanocontainer for Peptide Drug Delivery,” International Journal of Environmental Research and Public Health, 2015, 12(10), pp 12543-12555.

Prachi Anand, Alison O’Neil, Emily Lin, Trevor Douglas, Mande Holford, “Tailored Delivery of Analgesic Ziconotide across a Blood Brain Barrier Model Using Viral Nanocontainers,” Scientific Reports, 2015, 5.

Amy Servid, Paul Jordan, Alison O’Neil, Peter Prevelige, Trevor Douglas, “Location of the Bacteriophage P22 Coat Protein C-terminus Provides Opportunities for the Design of Capsid Based Materials,” Biomacromolecules, 2013, 14, pp 2989-2995.

Alison O’Neil, Peter E. Prevelige, and Trevor Douglas, “Stabilizing Viral Nano-Reactors for Nerve Agent Degradation,” Biomaterials Science, 2013, 1, pp 881-886.

Alison O’Neil, Gautam, Basu, Peter E. Prevelige, and Trevor Douglas, “Co-Confinement of Fluorescent Proteins: Spatially Enforced Communication of GFP and mCherry Encapsulated Within the P22 Capsid,” Biomacromolecules, 2012. 13, pp 3902-3907.

Alison O’Neil, Courtney Reichhardt, Benjamin Johnson, Peter E. Prevelige, and Trevor Douglas, “Genetically Programmed in vivo Packaging and Controlled Release of Protein Cargo from Bacteriophage P22,” Angwandte Chemie International Edition, 2011, 50(32), pp 7425-7428.

Courtney Reichhardt, Masaki Uchida, Alison O’Neil, Peter Prevelige, Trevor Douglas, “Templated Assembly of Organic-Inorganic Materials Using the Core Shell Structure of the P22 Bacteriophage,” Chemical Communications, 2011, (47), pp 6326-6328.

Sebyung Kang, Masaki Uchida, Alison O’Neil, Rui Li, Peter Prevelige, Trevor Douglas, “Implementation of P22 Viral Capsids as Nanoplatforms,” Biomacromolecules, 2010, 11(10), pp 2804-2809.